diff --git a/tests/fuzz/fuzz-build.py b/tests/fuzz/fuzz-build.py
new file mode 100755
index 0000000..82edfb1
--- /dev/null
+++ b/tests/fuzz/fuzz-build.py
@@ -0,0 +1,110 @@
+#!/usr/bin/env python3
+# SPDX-License-Identifier: Apache-2.0 OR GPL-2.0-or-later
+
+# Builds fuzzing variants. Run this from the toplevel directory.
+# Beware this will wipe build directories.
+
+# Requires honggfuzz and afl++ installed
+
+# Builds are:
+# * AFL (normal, asan, cmplog)
+# * honggfuzz (asan, msan, ubsan)
+# * -O0, with coverage
+
+import os
+import subprocess
+
+# reduce warning level since tests since gtest is noisy
+BASE_MESONFLAGS = "-Dwarning_level=2 -Ddefault_library=static --wipe".split()
+FUZZ_PROGRAMS = ["tests/fuzz/i2c-fuzz"]
+
+
+def build(
+    build_dir: str,
+    cc: str = None,
+    cxx: str = None,
+    cflags="",
+    cxxflags="",
+    opt="3",
+    env={},
+    mesonflags=[],
+):
+    env = os.environ | env
+    env["CFLAGS"] = cflags
+    env["CXXFLAGS"] = cxxflags
+
+    # Meson sets CC="ccache cc" by default, but ccache removes -fprofile-arcs
+    # so coverage breaks (ccache #1531). Prevent that by setting CC/CXX.
+    env["CC"] = cc if cc else "cc"
+    env["CXX"] = cxx if cxx else "c++"
+
+    meson_cmd = ["meson"] + BASE_MESONFLAGS + mesonflags
+    meson_cmd += [f"-Doptimization={opt}"]
+    meson_cmd += [build_dir]
+    subprocess.run(meson_cmd, env=env, check=True)
+
+    ninja_cmd = ["ninja", "-C", build_dir] + FUZZ_PROGRAMS
+    subprocess.run(ninja_cmd, env=env, check=True)
+
+
+def build_afl():
+    env = {
+        # seems to be required for afl-clang-lto?
+        "AFL_REAL_LD": "ld.lld",
+    }
+    cc = "afl-clang-lto"
+    cxx = "afl-clang-lto++"
+
+    # normal
+    build("bfuzz", cc=cc, cxx=cxx, env=env)
+    # ASAN
+    build(
+        "bfuzzasan",
+        cc=cc,
+        cxx=cxx,
+        mesonflags=["-Db_sanitize=address"],
+        env=env,
+    )
+    # cmplog
+    build("bcmplog", cc=cc, cxx=cxx, env={"AFL_LLVM_CMPLOG": "1"} | env)
+
+
+def main():
+    # No profiling, has coverage
+    build(
+        "bnoopt",
+        cflags="-fprofile-abs-path",
+        cxxflags="-fprofile-abs-path",
+        opt="0",
+        mesonflags=["-Db_coverage=true"],
+    )
+
+    # AFL
+    build_afl()
+
+    # Honggfuzz
+    # asan by default
+    build(
+        "bhf",
+        cc="hfuzz-clang",
+        cxx="hfuzz-clang++",
+        env={"HFUZZ_CC_ASAN": "1"},
+    )
+    # msan
+    build(
+        "bhf-msan",
+        cc="hfuzz-clang",
+        cxx="hfuzz-clang++",
+        env={"HFUZZ_CC_MSAN": "1"},
+    )
+    # ubsan
+    build(
+        "bhf-ubsan",
+        cc="hfuzz-clang",
+        cxx="hfuzz-clang++",
+        env={"HFUZZ_CC_UBSAN": "1"},
+    )
+
+
+if __name__ == "__main__":
+    main()