diff --git a/Makefile.am b/Makefile.am
index e967280..3994ff0 100644
--- a/Makefile.am
+++ b/Makefile.am
@@ -35,7 +35,7 @@
 TESTS = $(check_PROGRAMS)
 
 check_PROGRAMS = tests/test_eid tests/test_seq tests/test_bridge \
-		 tests/test_astlpc
+		 tests/test_astlpc tests/test_serial
 # We set a global LDADD here, as there's no way to specify it for all
 # tests. This means other targets' LDADDs need to be overridden.
 LDADD = tests/libtest-utils.a libmctp.la
diff --git a/tests/test_serial.c b/tests/test_serial.c
new file mode 100644
index 0000000..9c4da34
--- /dev/null
+++ b/tests/test_serial.c
@@ -0,0 +1,100 @@
+/* SPDX-License-Identifier: Apache-2.0 OR GPL-2.0-or-later */
+
+#define _GNU_SOURCE
+
+#include "config.h"
+
+#include "libmctp-log.h"
+#include "libmctp-serial.h"
+
+#ifdef NDEBUG
+#undef NDEBUG
+#endif
+
+#include <assert.h>
+#include <fcntl.h>
+#include <stdio.h>
+#include <string.h>
+#include <unistd.h>
+
+struct mctp_binding_serial_pipe {
+	int ingress;
+	int egress;
+
+	struct mctp_binding_serial *serial;
+};
+
+static int mctp_binding_serial_pipe_tx(void *data, void *buf, size_t len)
+{
+	struct mctp_binding_serial_pipe *ctx = data;
+	ssize_t rc;
+
+	rc = write(ctx->egress, buf, len);
+	assert(rc == len);
+}
+
+uint8_t mctp_msg_src[2 * MCTP_BTU];
+
+static void rx_message(uint8_t eid, void *data, void *msg, size_t len)
+{
+	uint8_t type;
+
+	type = *(uint8_t *)msg;
+
+	mctp_prdebug("MCTP message received: len %zd, type %d", len, type);
+
+	assert(sizeof(mctp_msg_src) == len);
+	assert(!memcmp(mctp_msg_src, msg, len));
+}
+
+int main(void)
+{
+	struct mctp_binding_serial_pipe _a, *a = &_a;
+	struct mctp_binding_serial_pipe _b, *b = &_b;
+	struct mctp *mctp;
+	int p[2][2];
+	int rc;
+
+	mctp_set_log_stdio(MCTP_LOG_DEBUG);
+
+	memset(&mctp_msg_src[0], 0x5a, MCTP_BTU);
+	memset(&mctp_msg_src[MCTP_BTU], 0xa5, MCTP_BTU);
+
+	rc = pipe(p[0]);
+	assert(!rc);
+
+	rc = pipe(p[1]);
+	assert(!rc);
+
+	mctp = mctp_init();
+	assert(mctp);
+
+	mctp_set_rx_all(mctp, rx_message, NULL);
+
+	/* Instantiate the A side of the serial pipe */
+	a->serial = mctp_serial_init();
+	assert(a->serial);
+	a->ingress = p[0][0];
+	a->egress = p[1][1];
+	mctp_serial_open_fd(a->serial, a->ingress);
+	mctp_serial_set_tx_fn(a->serial, mctp_binding_serial_pipe_tx, a);
+	mctp_register_bus(mctp, mctp_binding_serial_core(a->serial), 8);
+
+	/* Instantiate the B side of the serial pipe */
+	b->serial = mctp_serial_init();
+	assert(b->serial);
+	b->ingress = p[1][0];
+	b->egress = p[0][1];
+	mctp_serial_open_fd(b->serial, b->ingress);
+	mctp_serial_set_tx_fn(b->serial, mctp_binding_serial_pipe_tx, a);
+	mctp_register_bus(mctp, mctp_binding_serial_core(b->serial), 9);
+
+	/* Transmit a message from A to B */
+	rc = mctp_message_tx(mctp, 9, mctp_msg_src, sizeof(mctp_msg_src));
+	assert(rc == 0);
+
+	/* Read the message at B from A */
+	mctp_serial_read(b->serial);
+
+	return 0;
+}