diff --git a/config/ibm/50001000_v2.json b/config/ibm/50001000_v2.json
index 221b9c5..178d670 100644
--- a/config/ibm/50001000_v2.json
+++ b/config/ibm/50001000_v2.json
@@ -24,6 +24,28 @@
             }
         }
     },
+    "muxes": [
+        {
+            "i2bus": "4",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/4-0070/hold_idle"
+        },
+        {
+            "i2bus": "5",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/5-0070/hold_idle"
+        },
+        {
+            "i2bus": "6",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/6-0070/hold_idle"
+        },
+        {
+            "i2bus": "11",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/11-0070/hold_idle"
+        }
+    ],
     "frus": {
         "/sys/bus/i2c/drivers/at24/8-0050/eeprom": [
             {
diff --git a/config/ibm/50001001_v2.json b/config/ibm/50001001_v2.json
index afc5ecc..e522d46 100644
--- a/config/ibm/50001001_v2.json
+++ b/config/ibm/50001001_v2.json
@@ -24,6 +24,28 @@
             }
         }
     },
+    "muxes": [
+        {
+            "i2bus": "4",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/4-0070/hold_idle"
+        },
+        {
+            "i2bus": "5",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/5-0070/hold_idle"
+        },
+        {
+            "i2bus": "6",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/6-0070/hold_idle"
+        },
+        {
+            "i2bus": "11",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/11-0070/hold_idle"
+        }
+    ],
     "frus": {
         "/sys/bus/i2c/drivers/at24/8-0050/eeprom": [
             {
diff --git a/config/ibm/50003000_v2.json b/config/ibm/50003000_v2.json
index 0c4bfd1..71049eb 100644
--- a/config/ibm/50003000_v2.json
+++ b/config/ibm/50003000_v2.json
@@ -24,6 +24,23 @@
             }
         }
     },
+    "muxes": [
+        {
+            "i2bus": "5",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/5-0070/hold_idle"
+        },
+        {
+            "i2bus": "6",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/6-0070/hold_idle"
+        },
+        {
+            "i2bus": "7",
+            "deviceaddress": "0xE0",
+            "holdidlepath": "/sys/bus/i2c/drivers/pca954x/7-0070/hold_idle"
+        }
+    ],
     "frus": {
         "/sys/bus/i2c/drivers/at24/8-0050/eeprom": [
             {
diff --git a/ibm_vpd_app.cpp b/ibm_vpd_app.cpp
index 8acb03a..cff1a4f 100644
--- a/ibm_vpd_app.cpp
+++ b/ibm_vpd_app.cpp
@@ -1339,6 +1339,40 @@
 }
 
 /**
+ * @brief Function to bring MUX out of idle state
+ *
+ *        This finds All the MUX defined in the system json and enables
+ *        them by setting the holdidle parameter to 0.
+ * @param[in] js- system json to iterate through and take action
+ */
+void doEnableAllMuxChips(const nlohmann::json& js)
+{
+    // Do we have the mandatory "muxes" section?
+    if (js.find("muxes") != js.end())
+    {
+        std::cout << "Enabling all the MUX on the system " << std::endl;
+        // iterate over each MUX detail and enable them
+        for (const auto& item : js["muxes"])
+        {
+            if (item.find("holdidlepath") != item.end())
+            {
+                std::string holdidle = item["holdidlepath"];
+                std::cout << "Setting holdidle state for " << holdidle
+                          << "to 0 " << std::endl;
+                string cmd = "echo 0 > " + holdidle;
+                executeCmd(cmd);
+            }
+        }
+        std::cout << "Completed enabling all the MUX on the system "
+                  << std::endl;
+    }
+    else
+    {
+        std::cout << "No MUX was defined for the system" << std::endl;
+    }
+}
+
+/**
  * @brief Populate Dbus.
  * This method invokes all the populateInterface functions
  * and notifies PIM about dbus object.
@@ -1762,6 +1796,15 @@
             return 0;
         }
 
+        // Enable all mux which are used for connecting to the i2c on the pcie
+        // slots for pcie cards. These are not enabled by kernel due to an issue
+        // seen with Castello cards, where the i2c line hangs on a probe.
+        // To run it only once have kept it under System vpd check.
+        if (isSystemVpd)
+        {
+            doEnableAllMuxChips(js);
+        }
+
         try
         {
             variant<KeywordVpdMap, Store> parseResult;